Evaluation of the Presence of Enthesitis in Patients With Acne Vulgaris

Erol Olcok Corum Training and Research Hospital

Status: Unknown

Conditions: Enthesitis; Ultrasonography; Acne Vulgaris

Treatments: Diagnostic Test: ultrasonography

Study type: Observational

Funder types: Other

Identifiers

NCT04224597

Hitit University

Details and patient eligibility

About

Acne vulgaris is an inflammatory disease of the pilosebaceous unit, affecting about 85% of the young population. In the studies p. acne is a potent stimulator of the release of IFN-gamma (IFN-)) and IL-17 from CD4 + T cells, and the presence of IL-17 + cells in the perifollicular infiltrate has been shown in biopsies of inflammatory acne lesions. Therefore, acne is thought to be a Th17-related disease (1).

This study was aimed to evaluate the presence of enthesitis in patients with acne vulgaris.

Full description

Patients with acne vulgaris and healthy controls aged between 18-25 who admitted to Hitit University Erol Olcok Education and Research Hostpital Dermatology policlinic will be icluded. Patients with rheumatic, neurological diseases, history of trauma and previous fractures will be excluded from the study. After all the participants were evaluated by the dermatologist and demographic data will be recorded, the participants will be examined by the physical medicine and rehabilitation specialist and the short form-36 (sf-36), hospital anxiety and depression scale will be completed. Bilateral lower extremity tendon thicknesses and the presence of erosion, bursitis, etc. will be evaluated according to the criteria of Guess (Glasgow Ultrasound Enthesitis Scoring System) and Guess score will be determined for all participants. A total of 48 participants, 24 patients with acne vulgaris and 24 healthy controls, will be included in the study (2).

Enrollment: 48 estimated patients

Sex: Female

Ages: 18 to 25 years old

Volunteers: Accepts Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteira:

• Patients with acne vulgaris and healthy controls aged between 18-25

Exclusion Criteria:

• Participants with rheumatic and neurologic disease, history of trauma ,

Trial design

48 participants in 2 patient groups

Patients with acne vulgaris

Description:

patients with acne vulgaris aged between 18-25 year

Treatment:

Diagnostic Test: ultrasonography

Healthy controls

Description:

healthy controls aged between 18-25 year

Treatment:

Diagnostic Test: ultrasonography