Evaluation of the Remineralizing Effect of Aloe Vera Versus Diode Laser for Management of Deep Carious Lesions.

Al-Azhar University

Status: Completed

Conditions: Deep Caries

Treatments: Other: no intervention; Device: diode laser; Dietary Supplement: Aloe Vera

Study type: Interventional

Funder types: Other

Identifiers

NCT05327049

OPEN- 108-L

Details and patient eligibility

About

The present study will be performed to evaluate:

The remineralizing effect of Aloe Vera versus Diode laser on deep carious dentin after selective caries removal.

Full description

This study was conducted on 45 teeth selected from patients according to inclusion and exclusion criteria. They were selected from the dental clinic in faculty of oral and dental medicine for girls, Al-Azhar University. The procedure was explained and written informed consent was obtained from each patient. The possible discomforts, risks, and benefits were fully explained to the patients. Ethical committee approval was obtained.

Protocol of caries removal was Applied Subsequently, the central cariogenic biomasses and superficial part of the necrotic and demineralized dentin was excavated, leaving the leathery dentin layer.

Sample grouping:

The patients were randomly assigned into three main groups according to the material used (15 for each) which were assessed at different time intervals (B1) after three months,(B2) after six months.

A1: cavities will be sealed directly by temporary restorative material (conventional glass ionomer) without any treatment.

A2: cavities will be treated by Diode laser then sealed directly by temporary conventional glass ionomer.

A3: cavities will be treated with Aloe Vera then sealed directly by temporary conventional glass ionomer.

Evaluation of the remineralization effect of Each group will be assessed radiographically immediately at base line (B0), after three months (B1) and six months (B2) to evaluate the dentin remineralization.

Enrollment: 45 patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subject must have active deep carious lesion.
• clinical and radiographic examinations of carious lesions.

Exclusion criteria

• Teeth with pulpal involvement
• Teeth with abscess
• Teeth with pain or swelling
• Teeth with developmental disorders
• Teeth with adjacent soft tissue lesions
• patients with systemic illness will be excluded

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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45 participants in 3 patient groups

no intervention

Experimental group

Description:

No Intervention: conventional selective caries removal without treatment After taking the first sample of dentin, the cavity will be restored

Treatment:

Other: no intervention

diode laser treatment

Experimental group

Description:

After selective caries removal the cavity was irradiated in contact mode with continuous wave of radiation through a 400µm flexible fiber that was inserted inside the cavity with a spiral continuous movement clockwise from the top to the floor and anti-clockwise in the reverse direction. Irradiation time was 15 seconds and repeated three times for 15 seconds interval with contact, pulsed mode and the output power was adjusted at 1.30 Watt.

Treatment:

Device: diode laser

Aloe Vera treatment

Experimental group

Description:

After selective caries removal the lesions were treated with aloe Vera paste which was prepared by mixing aloe Vera powder by distilled water until a thick paste is formed. the paste was applied to the prepared floor by condenser to cover the remaining carious lesion

Treatment:

Dietary Supplement: Aloe Vera