Evaluation of the Renal Congestion, Perfusion and Function Before and After Diuretic Treatment in the ICU (ECHOFURO)

University Hospital, Strasbourg, France

Status: Unknown

Conditions: Renal Congestion

Treatments: Other: non applicable

Study type: Observational

Funder types: Other

Identifiers

NCT03704844

7148

Details and patient eligibility

About

Renal congestion is a pathological state that can lead to acute kidney failure. Furosemide is known to lower renal congestion by its diuretic effect.

The aim of this trial is to study the reversibility of kidney congestion under diuretic therapy and assess through echodoppler parameters if it can improve renal perfusion and function in congestive ICU patients.

It could in fine lead to a better identification of patients that could benefit from diuretic therapy in the ICU.

Enrollment: 120 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patient hospitalized in ICU
• under furosemide treatment

Exclusion criteria

• participation refusal
• uncontrolled shock (MAP<65mmHg)
• abdominal compartment syndrome
• diuretic administration in the 6 hours prior to inclusion
• renal replacement therapy or stage 4-5 chronic kidney disease
• atrial fibrillation
• no monitoring of CVP / invasive arterial pressure

Trial design

120 participants in 2 patient groups

Patients with renal congestion

Treatment:

Other: non applicable

Patients without renal congestion

Treatment:

Other: non applicable