Evaluation of the Retina of Subjects Without Diabetes Mellitus and Subjects With Diabetes Mellitus Without Diabetic Retinopathy Using Optical Coherence Tomography

Johns Hopkins University

Status: Completed

Conditions: Diabetic Retinopathy

Treatments: Other: OCT Imaging both Normal and diabetic groups

Study type: Observational

Funder types: Other

Identifiers

NCT01946997

03-11-05-03

Details and patient eligibility

About

The purpose of this study is to evaluate topographic features of the posterior pole of the eye in normal subjects as well as in subjects with diabetes mellitus but without diabetic retinopathy (DR) using optical coherence tomography (OCT). The investigators proposal is a novel study to determine retinal volume of normal and diabetic subjects without DR. Specifically, the investigators will establish a standardized reference range for retinal thickness and volume that will provide standards for OCT analysis of different clinical trials for retinal diseases.

Enrollment: 200 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Healthy retinas
• Willingness to sign informed consent to have OCT images taken.

Exclusion criteria

• No macular pathology
• No Diabetes

Trial design

200 participants in 2 patient groups

Group 1: Non Diabetic

Description:

Normal retina

Treatment:

Other: OCT Imaging both Normal and diabetic groups

Group 2: Diabetes with no retinopathy

Description:

Diabetic patients without diabetic retinopathy

Treatment:

Other: OCT Imaging both Normal and diabetic groups