Evaluation of the Role of Latent Toxoplasmosis in Female Patients With Active Acne Vulgaris

Sohag University

Status: Not yet enrolling

Conditions: Acne Vulgaris; Toxoplasmosis

Treatments: Diagnostic Test: Free testosterone levels and toxoplasma igG

Study type: Interventional

Funder types: Other

Identifiers

NCT05783778

Soh-Med-23-03-05MS

Details and patient eligibility

About

Acne vulgaris is one if the most common chronic inflammatory skin disorders.Acne is characterized by forming of inflammatory and non inflammatory lesions mainly on the Face,neck,arms, upper trunk and back

Full description

One of the hidden hormonal imbalance is Toxoplasma infection.Toxoplasmosis is a zoonotic infection the definite host is feline whereas human and other warm blooded animals are intermediate host . Endocrine alterations occuring during toxoplasmosis can be a hidden cause of acne vulgaris

Enrollment: 200 estimated patients

Sex: Female

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Female patients with active acne vulgaris

Exclusion criteria

• Patients with history of hormonal treatment Patients received anti toxoplasma therapy Patients with dermatological diseases caused by hormonal disturbances Pregnant and lactating patients

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

---

200 participants in 2 patient groups

Toxoplasmosis seropositive female patients with active acne vulgaris

Experimental group

Treatment:

Diagnostic Test: Free testosterone levels and toxoplasma igG

Toxoplasmosis seronegative in female patients with active acne vulgaris

Experimental group

Treatment:

Diagnostic Test: Free testosterone levels and toxoplasma igG