Evaluation of the Safety and Effectiveness of omniLenz in Patient With Ocular Graft vs Host Disease

Farwaniya Hospital

Status: Completed

Conditions: Ocular Graft Versus Host Disease

Treatments: Device: omniLenz

Study type: Interventional

Funder types: Other

Identifiers

NCT07066865

1630/2025

Details and patient eligibility

About

A case series of patients presented with graft versus host disease with ocular involvement . The study recruited a total of 3 patients who were referred to cornea clinic of Farwaniya Hospital, Kuwait between April 2022 and April 2024. All cases presented with severe dryness, spks and corneal epithelial defect not responding to other measures of treatment. An OmniLenz was applied for each patient for one week. Primary outcome measures included healing of the corneal resistant epithelial defect, secondary outcome measures were improvement of signs of dryness.

Enrollment: 3 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of Ocular graft versus host disease

Exclusion criteria

• Patient with conjunctival fibrosis and symblephara formation (which interfere with application of the omnilenz)

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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3 participants in 1 patient group

patient who applied OmniLenz for one week

Experimental group

Treatment:

Device: omniLenz