Evaluation of the Strip PeriScreen for the Fast Diagnosis of the Spontaneous Infection of the Liquid of Ascites During the Cirrhosis (Per-DRISLA)

Centre Hospitalier Departemental Vendee

Status

Completed

Conditions

Infection

Liquid of Ascites

Cirrhosis

Treatments

Other: strip Peri Screen

Study type

Interventional

Funder types

Other

Identifiers

NCT02085915

CHD 065-13

Details and patient eligibility

About

The forecast of the spontaneous infection of the liquid of ascites (ISLA) at the cirrhotic patient is still burdened by a heavy mortality. The fast diagnosis of the ISLA is thus an essential stake to improve the forecast.

Investigators would so like to estimate the interest of the strip PeriScreen for the fast diagnosis of the ISLA at cirrhotic patients . Investigators plan to include 670 patients, what would allow to make out a will at least on ascites 2000 on about twenty centers for duration estimated of 12 months.

Enrollment

670 patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Male or female over 18 years
Presence of ascites due to cirrhosis
Hospitalization for a complication of cirrhosis (ascites first decompensation, gastrointestinal bleeding, encephalopathy, etc ...).

Hospitalization to perform a paracentesis evacuated outpatient
Patients on long-term antibiotic primary or secondary prophylaxis the spontaneous bacterial peritonitis and with clinical and/or biological signs that suggest spontaneous infection of ascite.

Exclusion criteria

Patients with ascites urgently admitted to hospital for suspected infection receiving antibiotics for more than 12 hours.
chylous ascites,
Hemorrhagic Ascites
Biliary Ascites (straw)
Ascites heterogeneous appearance
Ascites not related to portal hypertension (peritoneal carcinomatosis, pancreatic ascites, tuberculosis, etc ...)
Patient receiving imipenem IV.
Patients on long-term antibiotic primary or secondary prophylaxis the spontaneous bacterial peritonitis without clinical and/or biological signs that suggest spontaneous infection of ascite.