Evaluation of the Use of Cefoxitin in Combination in Continuous Parenteral Administration in the Treatment of Bone and Joint Infections

Civil Hospices of Lyon

Status: Completed

Conditions: Antibiotic Reaction; Bone and Joint Infection

Treatments: Other: bone and joint infection treated with cefoxitin

Study type: Observational

Funder types: Other

Identifiers

NCT03848104

18-079

Details and patient eligibility

About

Cephamycin related to 2nd generation cephalosporins, the use of cefoxitin has long been limited to antibiotic prophylaxis. Because of its spectrum (sensitive staphylococci, enterobacteria including ESBL, streptococci, anaerobes), its stability and its low cost, it could be useful in curative bone and joint infections, especially in case of infection polymicrobial disease in patients for whom antibiotic alternative per os is limited.

Enrollment: 35 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients havind had a bon and joint infeciton treated with cefoxitin in combination in continuous parenteral administration

Exclusion criteria

Trial design

35 participants in 1 patient group

bone and joint infection treated with cefoxitin

Description:

patients having had a bone or joint infection treated by cefoxitin in combination. Cefoxitin has been administered by continuous way, at home. A serum dosage of cefoxitin has been systematically achieved at equilibrium.

Treatment:

Other: bone and joint infection treated with cefoxitin