Evaluation of Tolsura When Used as Prophylaxis After Lung Transplantation

Hong Nguyen

Status: Withdrawn

Conditions: Lung Transplant Infection

Treatments: Drug: Tolsura

Study type: Observational

Funder types: Other

Identifiers

NCT04652050

STUDY20080119

Details and patient eligibility

About

This is a single-center, observational study of Tolsura PK sampling in lung transplant recipients

Full description

Patients who are receiving Tolsura as part of their clinical care will be asked to enroll and EMR data and excess biological samples will be collected

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 18 years of age and older
• hospitalized at UPMC
• placed on Tolsura prophylactically by clinical team
• patients who have had or will have a lung transplant.

Exclusion criteria

• redo lung transplant
• recipient with dual liver-lung transplant
• patients with previous history of SOT
• including other organ transplantation
• patients with known pre-transplant colonization with moulds resistant to azoles
• patients with intra-transplant positive cultures for moulds in either transplant recipient or his/her donor
• patients with a history of hypersensitivity reaction to an azole agent
• patients who are kept NPO (nothing by mouth, including meds)
• recipients or donor with HepC PCR positive

Trial design

0 participants in 1 patient group

lung transplants

Description:

Lung transplants on Tolsura for infection

Treatment:

Drug: Tolsura