Evaluation of Topical Antipsoriatics in the Psoriasis Plaque Test

Technische Universität Dresden

Status: Completed

Conditions: Psoriasis Vulgaris

Treatments: Procedure: coherence tomography; Drug: Protopic, Advantan; Procedure: Blood and Urine Test

Study type: Interventional

Funder types: Other

Identifiers

NCT00236171

ETAPSO

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy of the topical therapies Protopic and Advantan as well as their combination against placebo in a Psoriasis Plaque Test

Full description

daily psoriasis plaque tests for two weeks and optical coherence tomography (OCT) and 20-MHz-ultrasound on day 0 and day 11, 10 days post end of treatment and 20 days post end of treatment

Enrollment: 14 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients older than 18 Years
• Negative urine pregnancy test
• Written informed consent
• Good compliance

Exclusion criteria

• Patients less than 18 years
• Pregnant patients
• Patients with renal insufficiency, liver diseases
• Patients who received systemic antipsoriatic treatment or UV treatment less than 4 weeks prior to study
• Patients who used topical antipsoriatics within two weeks prior to study
• Immunosuppressed Patients

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Single Group Assignment

Masking: Triple Blind