EVALUATION OF TREM-1, MMP-8 AND TIMP-1 LEVELS IN PERI-IMPLANT CREVİCULAR FLUID OF PERI-IMPLANTED INDIVIDUALS

Aydin Adnan Menderes University

Status: Completed

Conditions: Peri-implantitis; Peri-Implant Health

Treatments: Other: Collection of PICF samples

Study type: Observational

Funder types: Other

Identifiers

NCT07379892

BAP-23003

Details and patient eligibility

About

The aim of this study was to evaluate the relationship between TREM-1, MMP-8 and TIMP-1 levels in peri-implant crevicular fluid (PIOS) in peri-implantitis patients.

Full description

The aim of this study was to evaluate the relationship between TREM-1, MMP-8, and TIMP-1 levels in peri-implant groove fluid (PIOS) in patients with peri-implantitis, and the correlation of these markers with clinical periodontal parameters.

Enrollment: 54 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Systemically healthy
• Pregnancy or lactation

Exclusion criteria

• osteoporosis
• rheumatoid arthritis
• autoimmune disease
• diabetes

Trial design

54 participants in 2 patient groups

Peri-implantitis

Description:

Peri-implantitis is defined as bleeding on probing, suppuration, increased probing depth, clinical attachment loss, and radiographic bone loss

Treatment:

Other: Collection of PICF samples

Peri-implant Health

Description:

Peri-implant health is characterized by the absence of bleeding on probing, erythema, swelling, and suppuration in the peri-implant region

Treatment:

Other: Collection of PICF samples