Evaluation of Two Different Grafting Techniques After Mandibular Impacted Third Molar Surgery

Konya Necmettin Erbakan Üniversitesi

Status: Unknown

Conditions: Impacted Third Molar Tooth; Periodontal Pocket; Impacted Teeth With Abnormal Position

Treatments: Procedure: Impacted third molar surgery; Procedure: Application of β-tricalcium phosphate; Procedure: Application of mineralised plasmatic matrix

Study type: Interventional

Funder types: Other

Identifiers

NCT04366635

KonyaNEU1

Details and patient eligibility

About

This study evaluates the effectiveness of using Mineralized Plasmatic Matrix and β-tricalcium phosphate that placed to extraction socket as a graft material in terms of periodontal damage occurred in the distal aspect of the second molar after mandibular impacted third molar surgery.

Enrollment: 36 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Medically healthy.
• Periodontally healthy patients.
• Patients with mesioangular or horizontal impacted teeth that will cause periodontal damage at the distal part of the second molar after surgery.

Exclusion criteria

• Crowns on second molar teeth.
• Poor oral hygiene.
• Patients with a systemic disease affecting periodontal healing.
• Pregnancy or lactation period.
• Patients undergoing orthodontic treatment.
• Smokers.
• The cases where the buccal or lingual cortical bone didn't remain intact following the extraction were also excluded.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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36 participants in 3 patient groups

Mineralised Plasmatic Matrix Group

Experimental group

Description:

Mineralized Plasmatic Matrix (MPM) is a product of mixing of two phases: the mineral phase and the plasma phase. After centrifugation, the white blood cells are recovered and mixed with the mineral phase of bone graft that can be autogenic, allogeneic bone, or a bone substitute like Xenogeneic Bone Synthetic. We will use Beta-tricalcium phosphate as a graft material. The result of this mixture is a homogeneous single component, which is compact and stable, containing the graft, the dense fibrin network, and the promoting healing. And then we are planning to place MPM material to extraction socket of impacted third molar tooth to improve periodontal healing at the distal aspect of second molar tooth. Additional after MPM places to extraction socket, Once the MPM has been placed, it will be covered with a Platelet Rich Fibrin (PRF) membrane and sutured as a primer.

Treatment:

Procedure: Application of mineralised plasmatic matrix

Procedure: Impacted third molar surgery

Beta-tricalcium phosphate Group

Experimental group

Description:

Beta-tricalcium phosphate graft will place in the extraction socket and cover with a PRF membrane.

Treatment:

Procedure: Impacted third molar surgery

Procedure: Application of β-tricalcium phosphate

Control Group

Active Comparator group

Description:

In the control group, after removal of impacted third molar tooth no material will be placed on the extraction socket. Only the extraction socket was primarily closed with non-resorbable sutures.

Treatment:

Procedure: Impacted third molar surgery