Evaluation of Vitamin D Status in Children With Acute Burns (VitaminD)

Shriners Hospitals for Children

Status and phase

Completed

Phase 1

Conditions

Burns

Bone Demineralization

Treatments

Dietary Supplement: Vitamin D2

Dietary Supplement: Vitamin D3

Study type

Interventional

Funder types

Other

Identifiers

NCT00536276

01-9-26-1

Details and patient eligibility

About

To see which vitamin D supplement (D2 vs D3) is most beneficial in burned children.

Full description

The purpose of this study is to follow up our descriptive observations with a prospective randomized double blinded study to verify our clinical perception that hypovitaminosis D is prevalent postburn and to evaluate whether therapeutic supplementation will enhance specific primary outcome measures during burn convalescence.

Enrollment

50 patients

Sex

All

Ages

6 months to 18 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Child is > 6 months of age but < 19 years old
Burn injury > 30% total body surface area
Admitted to SHC within 4 days of injury
Attending physician decision that patient is likely to survive
Parents or legal guardian give informed consent along with assent of the child as applicable

Exclusion criteria

Attending physician decision that patient is not likely to survive
Prior history of anticonvulsant or glucocorticoid use, gastric/bowel resection, parathyroid disease, liver disease, chronic renal failure or prior pharmacologic vitamin D use (>1000 IU/D)