Evaluation, Treatment and Monitoring of Patients With a Known or Suspected Parasitic Infection

National Institute of Allergy and Infectious Diseases (NIAID)

Status: Enrolling

Conditions: Echiniococcus; Strongyloides; GI Protozoa; Intestinal Worms; Malaria

Study type: Observational

Funder types: NIH

Identifiers

NCT00001645

970096

97-I-0096

Details and patient eligibility

About

The purpose of this study is to evaluate, treat and follow patients with parasitic infections.

People with a known or suspected parasitic infection who are at least 1 year old may be enrolled. This study does not involve any experimental treatments.

Participants will have a physical examination and laboratory tests on blood, stool, or urine. Blood samples may be collected at regular intervals, but no more than 450 ml (15 ounces) of blood will be drawn from adults, and no more than 7 ml (1-1/2 teaspoons) per kg (2.2 pounds) of body weight from children, in any 6-week period. Other tests may include x-rays, electrocardiogram (EKG), or tissue biopsy (surgical removal of a small tissue sample), depending on the individual s condition.

Patients may be offered treatment or may be referred to another study that is more appropriate for the problem. Any treatment provided in this study will be according to standard medical practice for the patient s specific medical problem. Patients responses to treatment will be evaluated at regularly scheduled clinic visits. The length of time between visits and the total duration of the study for a given individual will be determined by the study doctor, based on that person s medical condition.

Full description

This study is designed as a prospective study to evaluate and treat patients with parasitic infection. Patients with known or suspected parasitic infection will be enrolled and will be evaluated for the presence of a parasitic infection. Minimal studies scheduled for each visit will include a medical history, physical examination, routine laboratory tests, and specialized diagnostic procedures for possible parasitic infections. Treatment plans will be individualized for each patient's particular condition, and the number and length of additional visits and diagnostic evaluations will vary accordingly. Specific treatment regimens will be in accordance with standard medical practice.

Enrollment: 500 estimated patients

Sex: All

Ages: 3+ years old

Volunteers: No Healthy Volunteers

Inclusion and exclusion criteria

• INCLUSION CRITERIA:

Age 3 or over.

Access to a primary medical care provider outside of the NIH

Clinical evidence suggestive of a parasitic infection

EXCLUSION CRITERIA:

Less than 3 years of age

No evidence suggestive of a parasitic infection

Trial design

500 participants in 5 patient groups

Diarrhea GI parasite

Description:

Subjects infected with a GI parasite

Echinococcus

Description:

Subjects infected with echinococcus

Intestinal worm

Description:

Subjects infected with parasitic intestinal worm

Malaria

Description:

Subjects infected with malaria

Parasitic infection

Description:

Subjects infected with a parasitic infection that is not included in the other cohorts