Evaluations of Optimizing Perioperative Fluid Management on Postoperative Pain Outcomes

Kaohsiung Veterans General Hospital

Status: Completed

Conditions: Patients Major Laminectomy Surgery

Treatments: Procedure: CVP-guided fluid management; Procedure: SVV-guided fluid management

Study type: Interventional

Funder types: Other

Identifiers

NCT02245581

VGHKS-102-036

Details and patient eligibility

About

Patient characteristics, duration of surgery, and infusion volumes will be compared between the groups. Oxygen transport and organ function will be compared Length of hospital stay, morbidity, postoperative pain intensity were compared. Continuous variables will be analyzed using the student t-test and discrete variables will be analyzed using Chi-Square test. P-value <0.05 will be considered significant, where appropriate 95% confidence intervals will be calculated. Statistical analysis will be carried out using standardize statistical programs SPSS 12.0 for windows.

Enrollment: 72 patients

Sex: All

Ages: 20+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• All patients are undergoing elective spine laminectomy

Exclusion criteria

• age <20 yr
• emergency surgery
• coagulopathy
• renal and hepatic dysfunction
• hyperthyroidism, and cardiac rhythm other than sinus rhythm

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

72 participants in 2 patient groups

SVV-guided fluid management

Active Comparator group

Description:

SVV : Stoke volume variation

Treatment:

Procedure: SVV-guided fluid management

CVP-guided fluid management

Active Comparator group

Description:

CVP : Central venous pressure

Treatment:

Procedure: CVP-guided fluid management