Evening Primrose Oil Efficacy in Second Trimester Abortion

Ain Shams University

Status and phase: Unknown; Phase 3

Conditions: Missed Abortion

Treatments: Drug: Evening primrose oil(EPO); Drug: Placebo - Cap

Study type: Interventional

Funder types: Other

Identifiers

NCT03698734

ASU obstetrics hosp

Details and patient eligibility

About

efficacy of evening primrose oil in shortening the duration of induction in 2nd trimesteric missed abortion

Enrollment: 100 estimated patients

Sex: Female

Ages: 18 to 35 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Primiparous women

Exclusion criteria

• Previous uterine incision( Cs, myomectomy,)
• Contraindications to medical or surgical uterine evacuations (eg, hemodynamically unstable, coagulopathy)
• Evidence of intra-uterine infection
• Rupture of fetal membranes.
• Intrauterine device in place.
• Allergy to prostaglandins or EPO

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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100 participants in 2 patient groups, including a placebo group

Evening primrose oil

Active Comparator group

Treatment:

Drug: Evening primrose oil(EPO)

placebo

Placebo Comparator group

Treatment:

Drug: Placebo - Cap