Evidence-based Screening Strategies for Celiac Disease

Katri Kaukinen

Status: Invitation-only

Conditions: Celiac Disease

Treatments: Diagnostic Test: Celiac disease antibody screening

Study type: Observational

Funder types: Other

Identifiers

NCT03136731

Celiac2017

Details and patient eligibility

About

Main aim: To find evidence-based screening strategies for celiac disease in high risk groups and to find new biomarkers or biomarker combinations for celiac disease diagnostics and follow-up.

Full description

The current project will result in the identification of genetic, environmental or downstream biomedical markers that predict the development of celiac disease at the individual level. Moreover, the markers can be exploited in prediction of specific disease risks, manifestations, comorbidities and complications.

Enrollment: 3,517 estimated patients

Sex: All

Ages: 6 months to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Cohort 1: Family member of celiac disease patient
• Cohort 2: Previously diagnosed celiac disease

Exclusion criteria

• Cohort 1: No previous celiac disease
• Cohort 2: Celiac disease diagnosis not confirmed

Trial design

3,517 participants in 2 patient groups

Healthy family members of celiac disease

Description:

Celiac disease screening, no intervention.

Treatment:

Diagnostic Test: Celiac disease antibody screening

Celiac disease index cases

Description:

Assessment of disease related factors, no intervention.