Evolution of Aqueous Flare in Rhegmatogenous Retinal Detachments Treated With Gas or Silicone Oil Tamponade. (FLADESIL)

Central Hospital, Nancy, France

Status: Completed

Conditions: Retinal Detachment

Treatments: Other: Aqueous flare measurement

Study type: Observational

Funder types: Other

Identifiers

NCT05053698

2020PI209

Details and patient eligibility

About

To examine and to compare the evolution of aqueous flare from presentation until the third postoperative month in a series of consecutive patients who underwent primary vitrectomy for rhegmatogenous retinal detachment (RRD), in 4 groups of patients :

• Group 1 : 48 eyes primarily treated with gas tamponade
• Group 2 : 11 eyes primarily treated with silicone oil tamponade
• Sub-Group G1RG : 8 eyes among Group 1 treated with gas after relapse
• Sub-Group G1RS : 3 eyes among Group 1 treated with silicone oil after relapse

Enrollment: 48 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• adult patients
• patients who underwent surgery for rhegmatogenous retinal detachment (silicone or gas tamponade)
• aqueous flare measurement carried out preoperatively and postoperatively at 2-4 weeks and 3 months

Exclusion criteria

• diabetic retinopathy
• glaucoma
• non rhegmatogenous retinal detachment
• active uveitis
• pseudoexfoliation syndrome.

Trial design

48 participants in 4 patient groups

Initial gas tamponade

Description:

Primary vitrectomy and fluid-air exchange with SF6 or C2F6 gas tamponade

Treatment:

Other: Aqueous flare measurement

Initial silicone oil tamponade

Description:

Primary vitrectomy and fluid-air exchange with silicone oil tamponade

Treatment:

Other: Aqueous flare measurement

Relapse treated with gas tamponade

Description:

Secondary vitrectomy and fluid-air exchange with SF6 or C2F6 or C3F8 gas tamponade

Treatment:

Other: Aqueous flare measurement

Relapse treated with silicone oil tamponade

Description:

Secondary vitrectomy and fluid-air exchange with silicone oil tamponade

Treatment:

Other: Aqueous flare measurement