Evolution of the Physical Condition in Treated Cancer Patients (PROTECT-01)

Centre Paul Strauss

Status: Unknown

Conditions: Breast Cancer Female; Colon Cancer; Non-small Cell Lung Cancer Metastatic

Treatments: Other: Adaptated Physical Activity

Study type: Interventional

Funder types: Other

Identifiers

NCT03956641

2019-A00848-49 (Other Identifier)

2019-001

Details and patient eligibility

About

Adaptated Physical Activity (APA) during treatment of cancer is one of the actual global health recommendation because of the benefits observed in several parameters evaluated in many clinical studies. A best knowledge of the physical and medical characteristics of patients, including type of cancer and type of treatment, is primordial to optimize the patient care and the effectiveness of APA programs.

Descriptive, explorative and prospective study of 3 different populations:

One population with locally advanced or metastatic non-small cell lung cancer treated with multiple therapeutic lines. Two different populations of early cancer patients and treated with a platinum-based regimen for colon cancer and a taxane-based chemotherapy for breast cancer.

Enrollment: 300 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Woman with breast cancer treated with adjuvant chemotherapy (taxane) or patient with colon cancer treated with adjuvant regimen (FOLFOX) or patient with locally advanced or metastatic lung cancer
• Patient without contraindication to the study-specific assessments
• Eastern Cooperative Oncology Group ≤ 2
• Age ≥ 18 years old
• Life expectancy > 6 months
• Able to speak, read and understand French
• Written informed consent obtained from the patient
• Registration in a national health care system

Exclusion criteria

• Patient with psychiatric, neurologic or musculoskeletal disorders
• Pregnant or breastfeeding women
• Minor or protected adult

Trial design

Primary purpose: Supportive Care

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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300 participants in 1 patient group

experimental: observational cohort

Experimental group

Description:

Evaluation of the physical condition and the quality of life

Treatment:

Other: Adaptated Physical Activity