Evolving Treatment Modalities for Management of Patients Suffering From Disc Displacement With Reduction

Nourhan M.Aly

Status: Completed

Conditions: Temporomandibular Joint Disc Displacement, With Reduction

Treatments: Drug: Botulinum toxin type A; Device: Low level laser therapy; Device: Anterior repositioning appliance

Study type: Interventional

Funder types: Other

Identifiers

NCT05194488

IRB 00010556

Details and patient eligibility

About

Aim of the current study is to compare the efficacy of Low Level Laser, Botulinum toxin type A, and repositioning appliance in management of reduced temporomandibular joint disc.

Enrollment: 27 patients

Sex: All

Ages: 20 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• TMJ with audible and palpable click.
• Patients with anterior disc displacement as detected by MRI.
• Presence of full or nearly full complement of natural teeth.

Exclusion criteria

• Patients who have radiographic evidence of degenerative conditions of TMJ.
• Patients who have anterior disc dislocation without reduction.
• Previous history of TMD treatment.
• History of recent trauma.
• The presence of systemic diseases (i.e. rheumatoid arthritis, osteoarthritis).
• Inability or unwillingness to undergo magnetic resonance imaging (MRI) such as implanted electronic devices.
• Pregnant and lactating females.
• Patients with known allergy to botulinum toxin type A.
• Patients suffering from neurological disorders.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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27 participants in 3 patient groups

Low level laser therapy

Experimental group

Treatment:

Device: Low level laser therapy

Botulinum toxin type A

Experimental group

Treatment:

Drug: Botulinum toxin type A

Anterior repositioning appliance

Active Comparator group

Treatment:

Device: Anterior repositioning appliance