Examination of ADMA Serum Level and DDAH II (ADSeS)

Universitätsklinikum Hamburg-Eppendorf

Status: Completed

Conditions: Septic Shock; Sepsis

Study type: Observational

Funder types: Other

Identifiers

NCT01632059

ADSeS (PV3927)

Details and patient eligibility

About

Examination of ADMA (Asymmetric-Dimethylarginine)-serum level and DDAH II (Dimethylarginine Dimethylaminohydrolase)- Polymorphism in patients with severe Sepsis and septic shock as prognostic value.

This study looks into ADMA as a good prognostic factor for sepsis. Further more the dependency of the ADMA level to the DDAH II polymorphisms is reviewed this study.

Full description

Secondary targets are the mortality (28 days ICU), the length of hospitalisation in ICU and peripheral station, the severity of the illness (SAPS II score), the SOFA-score values in the progress and the procalcitonin values in the progress

Enrollment: 120 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• >18 y/o
• sepsis
• septical shock

Exclusion criteria

• primary cardiogenic shock
• pregnancy
• breastfeeding
• non compliance
• moribund status

Trial design

120 participants in 1 patient group

septical patients

Description:

inclusion criteria are severe sepsis and septical shock and must be \> 18 y/o