Examination of B Cell Responses in Human Blood

Regenerative Medicine Network

Status: Completed

Conditions: HIV Infections

Study type: Observational

Funder types: Other; NETWORK

Identifiers

NCT00806845

RegMedNet-001

Details and patient eligibility

About

The aim of this study is the assessment B-cell immune responses in HIV-infected individuals.

Full description

Groups of patients with different immune competencies will be examined. The impact of HIV infection on immune response will be assessed.

Enrollment: 50 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• HIV-infected individuals
• controls

Exclusion criteria

• none

Trial design

50 participants in 5 patient groups

HIV infected individuals, HIV controllers

Description:

CD4+ T cell count \> 350/µl, HIV load \< 1000 copies/ml

HIV infected individuals, early progressors

Description:

CD4+ T cell count \> 350/µl, HIV load \> 1000 copies/ml

HIV infected individuals, late progressors

Description:

CD4+ T cell count \< 200/µl

HIV infected individuals, late progressors with therapy

Description:

CD4+ T cell count \< 200/µl, under ART

Healthy individuals

Description:

Uninfected