Examination of Cardiovascular Function/ Cardio Respiratory Interaction on Spontaneous Breathing Trials in Patients in the Prolonged Weaning (Weaning TTE)

RWTH Aachen University

Status: Unknown

Conditions: Cardiovascular Disease

Treatments: Other: Spontaneous breathing trial

Study type: Observational

Funder types: Other

Identifiers

NCT02569385

CTC-A 15-034

Details and patient eligibility

About

The aim of the present study is to determine the cardiovascular function/ cardio respiratory interaction on spontaneous breathing trials in patients with prolonged weaning.

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• legal Age (≥18 years)

• written informed consent Prior to study participation

• patient in prolonged weaning with NYHA I-II and an actual positive Ventilator Screening test:

  1. PaO2 ≥ 60 mmHg at FiO2 ≤ 0.4
  2. PEEP ≤ 8 cmH2O
  3. Glasgow Coma Scale > 13
  4. Temp. < 38°C
  5. Hb > 80-100 g/L
  6. less requirement on catecholamines (<0.1µg/kg/min)

• and on these patients are already performed a spontaneous breathing trial with following result:

  1. abortion this spontaneous breathing trial < 30min, but possible > 10min
  2. reason for an abortion was NOT hypercapnia

Exclusion criteria

• weaning patients are assigned on Group 1-2
• patient with heart failure (NYHA III-IV) and/ or other cardiac comorbidity
• acute NSTEMI (non-ST-segment elevation myocardial infarction)
• pregnancy and breast-feeding

Trial design

20 participants in 1 patient group

spontaneous breathing trials

Description:

spontaneous breathing trials in patients with prolonged weaning

Treatment:

Other: Spontaneous breathing trial