Examination of Serum Progesterone Levels in an IVF Population Following Two Types of Egg Aspiration

Red Rock Fertility Center

Status: Unknown

Conditions: Infertility, Female

Study type: Observational

Funder types: Other; Industry

Identifiers

NCT01513954

20111821

Details and patient eligibility

About

The purpose of this study is to determine whether progesterone hormone levels differ following egg retrieval with a single lumen needle compared with a double lumen needle. These levels will be measured on several days before and after egg retrieval. The progesterone levels in each IVF group will also be compared to the group of women who are having IUI. In addition, these progesterone levels will be correlated with pregnancy outcomes.

Full description

This is a prospective randomized trial consisting of 3 groups of patients. Following a long lupron protocol IVF cycle there is a need for supplemental progesterone. The purpose of this study is to determine what range of serum levels should be observed when differing methods of egg aspiration have been administered and whether or not there is a correlation with outcomes or pregnancies.

Enrollment: 450 estimated patients

Sex: Female

Ages: 21 to 37 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Ages between 21-37
• Cycle Day 3 FSH between 2-12
• History of regular menstrual cycles between 24-34 days

Exclusion criteria

• Previous IVF failure
• Severe male factor
• Severe obesity, BMI > 40
• More than 20 follicles on ultrasound prior to retrieval

Trial design

450 participants in 2 patient groups

IVF population

Description:

Long Lupron IVF Population

IUI patients

Description:

Patients undergoing IUI