Examination of the Effects of Four Different Spices on Energy Metabolism

University of Copenhagen

Status: Completed

Conditions: Healthy

Treatments: Dietary Supplement: black pepper; Dietary Supplement: ginger; Dietary Supplement: horseradish; Dietary Supplement: placebo; Dietary Supplement: mustard

Study type: Interventional

Funder types: Other

Identifiers

NCT00611156

B228-IHE-2006-NTG

Details and patient eligibility

About

The objective of this study is to examine whether four different spices (ginger, black pepper, horseradish and mustard) are able to increase energy metabolism.

Since chili and other spices have been shown to increase energy expenditure compared to placebo, we expect that some or all of the four spices may actually increase energy expenditure - although not to a large degree.

Full description

Several pungent food ingredients, such as chili,and also other bioactive food ingredients, e.g. green tea, have been shown to be able to increase energy expenditure and fat oxidation during the hours following a meal containing the bioactive ingredient. Furthermore, we will also look at the subjects own feelings of appetite and thereby examine whether the appetite is affected by the spicy food. We expect to see some small effects on these parameters.

Enrollment: 22 patients

Sex: Male

Ages: 18 to 50 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• male
• healthy and not use medication (regularly)
• normal weight
• non smoker
• tolerate and like spicy food
• stable body weight last two months

Exclusion criteria

• increased blood pressure
• abnormal EKG
• mental, metabolic and chronic diseases

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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22 participants in 5 patient groups, including a placebo group

A

Experimental group

Description:

Spice

Treatment:

Dietary Supplement: ginger

B

Experimental group

Description:

Spice

Treatment:

Dietary Supplement: black pepper

C

Experimental group

Description:

Spice

Treatment:

Dietary Supplement: horseradish

D

Experimental group

Description:

Spice

Treatment:

Dietary Supplement: mustard

E

Placebo Comparator group

Description:

Placebo

Treatment:

Dietary Supplement: placebo