Examination of the Time Advantage Between POCT and Conventional Central Laboratory Analysis

Johann Wolfgang Goethe University Hospital

Status: Completed

Conditions: Analysis, Event History; Blood; Point-of-Care Systems

Treatments: Diagnostic Test: POCT and central laboratory blood analysis

Study type: Observational

Funder types: Other

Identifiers

NCT03242525

279/17

Details and patient eligibility

About

The aim of the present study is to quantify the time advantage achieved by the use of POCT compared to conventional coagulation diagnostics. A further objective of this study is an analysis of the result quality of POCT for the prothrombin time / international normalized ratio.

Full description

In order to be able to carry out a targeted coagulation therapy for the time-critical treatment of coagulopathic emergency patients, knowledge of the hemostatic potential is necessary.

After taking blood samples for coagulation diagnostics, they are sent to the central laboratory. After the analysis and validation the electronic provision of the results takes place. The loss of time by sample transport, analysis and breadth of the results extends the duration until therapy can be started.

The period of time until these analysis results are determined depends on several factors like daytime, day of week and location of the sample consignor and the availability of the laboratory. Not every clinic is connected to an internal tube mail system so that the samples have to be sent partly with a transport service.

In recent years, Point of Care (POCT) devices have become an increasingly important tool for diagnosing coagulopathic patients.

Enrollment: 24 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Age > 18 years

Exclusion criteria

• Missing written consent
• Withdrawal

Trial design

24 participants in 2 patient groups

Emergency room

Description:

Twelve bleeding patients who are assigned to the emergency department receive a simultaneous blood analysis with POCT and central laboratory.

Treatment:

Diagnostic Test: POCT and central laboratory blood analysis

Delivery room

Description:

Twelve bleeding patients who are assigned to the delivery room receive a simultaneous blood analysis with POCT and central laboratory.

Treatment:

Diagnostic Test: POCT and central laboratory blood analysis