Examining Endogenous Antioxidant Levels in Well Trained Cyclists

University of Birmingham

Status: Completed

Conditions: Oxidative Stress

Study type: Observational

Funder types: Other

Identifiers

NCT02281851

13/WM/0226 (Other Identifier)

125663

Details and patient eligibility

About

This study will investigate whether increased habitual intake of antioxidant supplements effects the concentration of endogenous antioxidants, the response of antioxidants to exercise, and differences in oxidative damage compared to a non-supplemented group.

Enrollment: 14 patients

Sex: Male

Ages: 18 to 35 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Male,
• BMI 18.8 29.9 kg/m2
• cycle 3-7 times a week for durations longer than 60 minutes
• cycled for a minimum of 3 years
• accustomed to exhaustive cycling protocols
• healthy (no known cardiovascular or metabolic disease)

Exclusion criteria

• answering "NO" to any question on the general health questionnaire would result in exclusion from the study
• current participation in another clinical study
• current or recent smoker (last 30 days)
• prescription or non-prescription of anti-inflammatory use >30 days prior to the experiment commencing or any other medications that in the opinion of the investigator may interfere with redox signalling

Trial design

14 participants in 2 patient groups

Supplemented

Description:

The group consists of well-trained cyclists who habitually consume vitamin/antioxidant supplements for a period longer than 6 months

Non-supplemented

Description:

The group consists of well-trained cyclists who do not consume vitamin/antioxidant supplements