Examining the Association Between Pre-existing Sleep Disturbance and Postoperative Delirium

Mass General Brigham

Status: Completed

Conditions: Delirium

Treatments: Device: PSG

Study type: Observational

Funder types: Other

Identifiers

NCT03498560

2018P000480

Details and patient eligibility

About

The investigators are performing this research study to understand the role of sleep disturbance on the incidence/severity of delirium after surgery. The investigators will study the brain using a polysomnography device (PSG), which records the brain's electrical activity during sleep.

Full description

During this study, PSG recordings will be collected and a sleep questionnaire will be administered to participants on the night before surgery in order to establish level of preexisting sleep disturbance. Delirium assessments will be conducted during the postoperative period. On postoperative days 0 and 1, blood will be collected for analysis. Further cognitive, quality of life and pain questionnaires will be administered perioperatively.

Enrollment: 38 patients

Sex: All

Ages: 60 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Over 60 years of age
• Inpatient and scheduled for surgical procedure at MGH

Exclusion criteria

• Blindness, deafness or the inability to speak English
• Inability to provide informed consent

Objective Drop Criteria

• Post-operative intubation greater than 24 hours

Trial design

38 participants in 1 patient group

MGH Surgery Patients

Description:

PSG data will be collected, and delirium assessments conducted, on patients undergoing surgery at MGH.

Treatment:

Device: PSG