Examining The Effect of Blood Flow Restricted Aerobic Training on Mitochondrial Adaptations in Young Healthy Adults

Brendon Gurd, PhD

Status: Completed

Conditions: Mitochondrial Biogenesis

Treatments: Other: BFR Exercise Training; Other: CTL Exercise Training

Study type: Interventional

Funder types: Other

Identifiers

NCT04151095

BFRT

Details and patient eligibility

About

This parallel-arm trial study investigates the effects of restricting arterial blood flow during cycling exercise on citrate synthase. Participants will be randomized to either a blood flow restricted or non-blood flow restricted exercise training group. Both groups will complete seven, 30-minute exercise sessions over a 14-day period.

Enrollment: 19 patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• 3 hours of physical activity per week
• No previous cycling training
• No concurrent involvement in another training program
• Body mass index < 30 kg/m2

Exclusion criteria

• Presence of cardiovascular disease
• Presence of metabolic disease
• Taking regular oral medication
• Current smoker

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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19 participants in 2 patient groups

BFR

Experimental group

Treatment:

Other: BFR Exercise Training

CTL

Experimental group

Treatment:

Other: CTL Exercise Training