Excimer Light in Psoriasis

Cairo University (CU)

Status: Completed

Conditions: Psoriasis

Treatments: Device: Excimer light

Study type: Interventional

Funder types: Other

Identifiers

NCT05283876

Excimer light in psoriasis

Details and patient eligibility

About

The aim of this study is to determine the standard tissue levels of SP and its receptor in lesional skin of psoriasis patients in both developing and stationary stages before and after excimer light therapy.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type of Psoriasis: plaque psoriasis.
• Less than 10% surface area.

Exclusion criteria

• Erythrodermic psoriasis
• Pustular psoriasis
• Topical treatment for psoriasis for the past 2 weeks.
• Systemic retinoids in the last 2 years.
• Systemic treatments (including any drugs that affect SP level as Aprepitant) in the last 3 months.
• Contraindications to excimer light therapy (history of skin malignancy or precancerous conditions like xeroderma pigmentosum or photosensitivity)

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

Active psoriasis

Active Comparator group

Treatment:

Device: Excimer light

Stable psoriasis

Active Comparator group

Treatment:

Device: Excimer light