Exercise Adherence and Cognitive Decline (MOVE)

University of Colorado Boulder (CU)

Status: Enrolling

Conditions: Cognitive Decline

Treatments: Behavioral: Goal Setting and Exercise Intensity Intervention

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT06769022

23-01-0205

1R61AG078088-01A1 (U.S. NIH Grant/Contract)

Details and patient eligibility

About

The purpose of this study is to conduct a small-scale test of a goals-based program to help people to exercise more and learn what people like or don't like about the procedures. This program is being designed for individuals aged 45-65 from the Black community. Low levels of physical activity are related to health problems such as heart disease, diabetes, and cognitive decline. People of color are more negatively impacted by these conditions and have also historically been underrepresented by research seeking to increase physical activity. The investigators have developed this goals-based exercise promotion program with the help of a Black-led community-based organization (The Gyedi Project) and a Community Advisory Board made up of stakeholders in the Black community, and now the investigators are conducting a trial of its feasibility and acceptability.

Enrollment: 20 estimated patients

Sex: All

Ages: 45 to 65 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• <3 incorrect responses on the Pfeiffer Mental Status Questionnaire
• Ages 45-65.
• Consent to be randomized to condition.
• Planning to remain in the Denver metro area for the next two months
• Identify as Black or African American

Exclusion criteria

• Currently physically active (i.e., >90 min/week of moderate PA or >40 min/week of vigorous PA consistently for the past 6 months).
• On antipsychotic medications or currently under treatment for any serious psychiatric disorder, including Alzheimer's or dementia
• Answers "yes" to 1 or more of the 7 questions of the PAR-Q+
• Blood pressure at baseline or before exercise is greater than 140/90
• Blood pressure >210/90 mmHg (for men) or >190/90 mmHg (for women) immediately after exercise
• Inability to walk 3 blocks without chest pain, shortness of breath, or light headedness.
• Inability to climb 2 flights of stairs without chest pain, shortness of breath, or light headedness.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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20 participants in 4 patient groups

Moderate Intensity Exercise, Basic Goal Difficulty

Experimental group

Description:

Participants are assigned to exercise at a moderate intensity and create basic goals.

Treatment:

Behavioral: Goal Setting and Exercise Intensity Intervention

Moderate Intensity Exercise, Challenging Goal Difficulty

Experimental group

Description:

Participants are assigned to exercise at a moderate intensity and create challenging goals.

Treatment:

Behavioral: Goal Setting and Exercise Intensity Intervention

Vigorous Intensity Exercise, Basic Goal Difficulty

Experimental group

Description:

Participants are assigned to exercise at a vigorous intensity and create basic goals.

Treatment:

Behavioral: Goal Setting and Exercise Intensity Intervention

Vigorous Intensity Exercise, Challenging Goal Difficulty

Experimental group

Description:

Participants are assigned to exercise at a vigorous intensity and create challenging goals.

Treatment:

Behavioral: Goal Setting and Exercise Intensity Intervention