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The objective of the study is to evaluate the feasibility of a combined mobile health exercise and cognitive rehabilitation intervention and its effect on cognition in a single-arm pilot study that recruits cancer survivors.
Full description
Cancer survivors (i.e., those who completed cancer-directed treatment) often experience long-term treatment-related effects, such as cancer-related cognitive decline (CRCD). Exercise and cognitive rehabilitation (rehab) interventions have been shown to improve CRCD symptoms in both cancer and non-cancer populations. Among older adults without cancer, studies have also demonstrated that multicomponent interventions combining exercise and cognitive rehab are more effective in improving cognitive dysfunction than either intervention alone. However, exercise adherence and self-efficacy are lower in older adults compared to younger adults, and combined interventions may be too demanding for older cancer survivors. Therefore, innovative ways are needed to integrate an exercise program within the context of a cognitive rehab program to increase exercise adherence and self-efficacy, and ultimately improve CRCD symptoms through a streamlined multicomponent intervention.
In this study, the investigators propose to refine a multicomponent Exercise and COgnitive rehab intervention (E-Co) and assess its feasibility in older cancer survivors.
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Inclusion criteria
Age ≥60 years at the time of consent
Have a diagnosis of any cancer
Have completed curative intent treatments
Have concerns about memory or other thinking abilities following cancer treatment*
English speaking (because the interventions are available in English language only)
Eastern Cooperative Oncology Group (ECOG) performance status of 0-3
No medical contraindications for exercise per oncologist
Able to walk 4 meters
Able to provide informed consent
Exclusion criteria
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Interventional model
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20 participants in 1 patient group
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Central trial contact
Allison Magnuson; Kah Poh Loh
Data sourced from clinicaltrials.gov
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