Exercise and Diet in Type 2 Diabetic Women

Eulji University Hospital

Status: Completed

Conditions: Type 2 Diabetes; Insulin Sensitivity

Treatments: Behavioral: Exercise; Behavioral: Standard life style modification for type 2 diabetes; Behavioral: Diet and exercise; Behavioral: Diet restriction

Study type: Interventional

Funder types: Other

Identifiers

NCT00763074

Obesity_2006_1

Details and patient eligibility

About

The purpose of this study was to evaluate the effects of 12 weeks' increased daily physical activity versus diet restriction on regional fat distribution, insulin sensitivity and adipokines including retinol binding protein-4 (RBP-4), leptin, adiponectin, and a new marker, adiponectin to leptin ratio (AL ratio), in type 2 diabetic women.

Enrollment: 70 patients

Sex: Female

Volunteers: No Healthy Volunteers

Inclusion criteria

• Type 2 diabetic patient
• BMI>23kg/m2
• Female

Exclusion criteria

• The patients with co-morbidity such as heart failure, chronic kidney disease or liver cirrhosis

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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70 participants in 4 patient groups, including a placebo group

Control

Placebo Comparator group

Description:

Conventional education of life style intervention for type 2 diabetes

Treatment:

Behavioral: Standard life style modification for type 2 diabetes

Diet

Active Comparator group

Description:

Dietary calorie restriction

Treatment:

Behavioral: Diet restriction

Exercise

Active Comparator group

Description:

Encourage to increase exercise amount: more than 60min's of exercise with moderate activity level two times per day

Treatment:

Behavioral: Exercise

Diet and exercise

Active Comparator group

Description:

Intervention for both of exercise and diet

Treatment:

Behavioral: Diet and exercise