Exercise and Endocannabinoids for Brain and Mental Health (EMBH)
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Details and patient eligibility
About
This study will explore how exercise affects brain chemicals called endocannabinoids, which may improve thinking skills and reduce feelings of stress, anxiety, and low mood in children and teens aged 9 to 17. Participants will take part in a single 30-minute activity session, where they will be randomly assigned to one of three groups:
- Moderate-intensity exercise (walking or running on a treadmill at 50-70% of their maximum heart rate).
- Light stretching (gentle movements at less than 40% of their maximum heart rate).
- Seated meditation (relaxing without movement at less than 30% of their maximum heart rate).
The investigators will measure endocannabinoid levels, thinking skills, and mood before and after the activity to see how these activities affect the brain and emotions.
Enrollment
Sex
Ages
Volunteers
Inclusion criteria
- Provision of signed and dated informed consent form
- Stated willingness to comply with all study procedures and available for the duration of the study
- 9-17 years of age
- Adolescent and parent/guardian are English-speaking, as study assessments are in English
- Right-handed
Exclusion criteria
- Head injury
- Sensory (e.g., hearing) impairment
- Physical (e.g., motor, balance) impairment
- Physical disabilities
- Neurological disorders
- Any condition that would contraindicate blood draws
Trial design
Primary purpose
Allocation
Interventional model
Masking
68 participants in 3 patient groups
Trial contacts and locations
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Data sourced from clinicaltrials.gov
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