Exercise and RP (AVAMC and Emory)

Emory University

Status: Completed

Conditions: Retinitis Pigmentosa

Treatments: Other: Spin exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03381235

IRB00093690

Details and patient eligibility

About

The purpose of this study is to look in humans at the relationship between moderate or little exercise and their potential effects on the retina in patients with Retinitis Pigmentosa (RP).

Full description

Human studies have shown that regular exercise may have positive effects on common degenerative diseases such as Alzheimer's disease. Exercise has also shown to improve conditions the eye such as macular degenerations, glaucoma, and cataracts. Mice with retinal degeneration which were exposed to exercise showed that it helped to slow the rate of degeneration. The purpose of this study is to look in humans at the relationship between moderate or little exercise and their potential effects on the retina in patients with Retinitis Pigmentosa (RP).

Enrollment: 4 patients

Sex: All

Ages: 18 to 60 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Visual field no less than 10 degrees;
• VA no worse than 20/200 in the better seeing eye.

Exclusion criteria

• Not able to tolerate exercise due to an underlying medical condition.

Trial design

Primary purpose: Prevention

Allocation: Non-Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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4 participants in 2 patient groups

Moderate exercise

Experimental group

Description:

Subjects in the moderate exercise group will participate in Spin exercise designed by Dr. Nocera.

Treatment:

Other: Spin exercise

Mild exercise

No Intervention group

Description:

Sessions will be focused on balance and stretching.