Exercise and Severe Depression: Clinical and Biological Analysis

Hospital de Clinicas de Porto Alegre

Status

Completed

Conditions

Depression

Treatments

Other: Exercise

Study type

Interventional

Funder types

Other

Identifiers

07-438

Details and patient eligibility

About

The study aimed to evaluate the use of exercise as a complementary strategy to treat severe major depression in inpatients.

Hypothesis: Exercise can be used as a safe and efficacious complimentary strategy in severe depressed inpatients.

Enrollment

50 patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis of Major Depressive Disorder according to M.I.N.I (DSM-IV) criteria American Psychiatry Association(1994)
score of 25 or more on Hamilton-17
not being involved in other physical activity programs during the hospitalization
aged between 18 and 60 years
being able to read, understand, and provide written informed consent

Exclusion criteria

have three or more cardiovascular risk factors according to Physical Activity Readiness Questionnaire (PAR-Q)
are unable to exercise due other clinical condition
have diagnosis of Schizophrenia, Bipolar disorder or current use of alcohol or other drugs according to M.I.N.I DSM-IV criteria American Psychiatry Association(1994)
if they are taking beta-blocking medications