Exercise and Systemic Lupus Erythematosus

University of Sao Paulo

Status: Unknown

Conditions: Systemic Lupus Erythematosus

Treatments: Behavioral: Exercise training

Study type: Interventional

Funder types: Other

Identifiers

NCT01515163

Lupus and exercise

Details and patient eligibility

About

The investigators hypothesize that a three-month aerobic exercise training program will positively affect the lipid profile, insulin sensitivity , cytokine profile, the cardiovascular parameters and muscle strength in SLE patients.

Enrollment: 90 patients

Sex: Female

Ages: 7 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age between 7 and 40 years
• SLEDAI ≤ 4

Exclusion criteria

• Cardiovascular dysfunction
• Rhythm and conduction disorders
• Musculoskeletal disturbances
• Kidney and pulmonary involvements
• Peripheral neuropathy
• Use of tobacco
• Treatment with lipid-lowering or hypoglycemic drugs
• Fibromyalgia
• Use of chronotropic or antihypertensive drugs
• Physically active subjects

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 3 patient groups

Exercise

Experimental group

Description:

3-month exercise training program

Treatment:

Behavioral: Exercise training

Control

No Intervention group

Description:

Control group

Healthy control

Experimental group

Treatment:

Behavioral: Exercise training