Exercise as Cardio Protective Modulates in Diabetic Patients

King Saud University

Status

Completed

Conditions

Diabetes Mellitus

Exercise

Treatments

Other: Supervised aerobic exercise

Study type

Observational

Funder types

Other

Identifiers

NCT03925519

RRC-2013-010

Details and patient eligibility

About

Physical exercise for 6 months produced significant improvement in adiponectin, hs-CRP, and nitric oxide (NO) and was significantly correlated with adiposity markers, lipid profile and glycemic control factors in both obese and non-obese diabetic patients.
Patients with good physical activity reported a significant decrease in BMI, CHD risk scores, reduced hs-CRP, an increase in the levels of adiponectin and nitric oxide.
In patients with type 2 diabetes mellitus, adiposity markers, lipid profile, hs-CRP, and adiponectin were significantly improved following moderate exercise interventions

Full description

To elucidate the potential role of exercise as anti-adiposity and anti-cardio protective modulates, we thought to investigate the effect of supervised aerobic training of moderate intensity on adiposity markers, nitric oxide level, plasma adiponectin, hs-CRP, and its association with CHD risk score in obese and non-obese patients with type 2 diabetes.

Enrollment

50 patients

Sex

All

Ages

45 to 70 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

patients with type 2 diabetes for more than 5 years.
Patients who were diagnosed according to the criteria of the American diabetes association.
Not receiving any drugs affecting the data obtained
had Normal daily diets
Not participating in any other exercise programs
Without any musculoskeletal disorders affecting an exercise program

Exclusion criteria

Exclusion criteria included anemia, overt complications of diabetes like nephropathy, neuropathy, retinopathy, obvious ischemic heart disease (angina, myocardial infarction, and lead electrocardiogram abnormalities), HCV, HBV, chronic liver and kidney diseases, hypothyroidism, and drugs (diuretics; oral contraceptives).