Exercise Capacity in Bronchiectasis Resection

University of Sao Paulo

Status: Unknown

Conditions: Bronchiectasis

Study type: Observational

Funder types: Other

Identifiers

NCT01268475

CAPPesq 0671/10

Details and patient eligibility

About

Bronchiectasis can be defined as an abnormal and irreversible dilatation of the bronchial tree due to repeated cycles of inflammation and infection, resulting in progressive loss of lung function. The surgical treatment by pulmonary resection or even lung transplantation is indicated in cases of bronchiectasis primary nonresponsive to appropriate medical treatment, or when associated with serious complications. There are few literature data on the influence of bronchiectasis in exercise capacity, quality of life and functional capacity, and the impact of lung resection in patients with this diagnosis. The primary objective of this study is to evaluate prospectively the impact of lung resection on exercise capacity in patients with clinical and radiological diagnosis of bronchiectasis. The secondary objective of this study is to evaluate the impact of lung resection on quality of life and lung function and to analyze the the presence of predictors of postoperative functional deterioration and the occurrence of complications.

Enrollment: 30 estimated patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical and radiographic diagnosis of bronchiectasis;
• Lack of adequate response to clinical treatment after 1 year of follow-up and / or presence of disease complications;
• Agreement to participate of the study by signing of the Informed Consent Term

Exclusion criteria

• Comorbidities that prevent the patient to undergo general anesthesia;
• Musculoskeletal and/or psychomotor disability to perform pulmonary function tests and cardiopulmonary exercise tests;
• Inability to understand the quality of life questionnaires;
• Age over 90 years or less 18 years.