Exercise Capacity in COPD

Klinik für Kardiologie, Pneumologie und Angiologie

Status: Unknown

Conditions: Chronic Obstructive Pulmonary Disease

Treatments: Other: Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing

Study type: Observational

Funder types: Other

Identifiers

NCT03889964

17-033

Details and patient eligibility

About

In this study, cardiopulmonary exercise will be assessed to characterize the relevance of severity of COPD and coexisting cardiovascular comorbidities for exercise capacity.

Full description

In patients with chronic obstructive pulmonary disease (COPD) the interpretation of dyspnoea also needs to consider coexisting cardiovascular disease. Cardiopulmonary exercise testing (CPET) is used to characterize pulmonary and cardiac function and limitations during exercise. The investigators hypothesise that cardiopulmonary exercise is reduced in COPD patients with coexisting cardiovascular disease as well as in more symptomatic patients and in patients with frequent exacerbations. For this purpose, 100 patients with with stable COPD are characterized by clinical characteristics, laboratory tests, lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing.

Enrollment: 100 estimated patients

Sex: All

Ages: 40 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• patients with stable chronic obstructive pulmonary disease, exacerbated or stable
• 40-80 years
• sinus rhythm
• informed written consent

Exclusion criteria

• Inability to give written consent
• acute myocardial infarction with ST-segment elevations in last 30 days
• severe acute or chronic renal dysfunction
• severe heart failure-
• atrial fibrillation
• severe valve disease
• severe hypoxemia
• long term oxygen therapy or non invasive ventilation

Trial design

100 participants in 1 patient group

patients with stable COPD

Treatment:

Other: Measurement of lung function, electrocardiography, echocardiography and cardiopulmonary exercise testing