Exercise During the Allogeneic Stem Cell Transplantation

Charité University Medicine Berlin

Status and phase: Unknown; Phase 3

Conditions: Fatigue; Allogeneic Stem Cell Transplantation

Treatments: Other: Supervised exercise; Other: Exercise Instruction

Study type: Interventional

Funder types: Other

Identifiers

NCT00883714

EA4/030/09

Details and patient eligibility

About

The study will evaluate the effects of a structured endurance exercise program on the physical performance, the mood and the complications of patients with hematological malignancies undergoing a high-dose chemotherapy followed by an allogeneic peripheral blood stem cell transplantation.

Enrollment: 60 estimated patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Neoplastic malignancy
• Allogeneic peripheral stem cell transplantation
• Proficiency in German

Exclusion criteria

• Cardiorespiratory, metabolical, osteoarticular or immunological disorders which can be aggravated by exercise
• Pathological stress-ECG at admission

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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60 participants in 2 patient groups

Supervised exercise

Experimental group

Treatment:

Other: Supervised exercise

Control group

Active Comparator group

Treatment:

Other: Exercise Instruction