Exercise Effects on Sarco-Osteopenia in Older Men

University of Erlangen-Nürnberg Medical School

Status: Completed

Conditions: Osteopenia; Sarcopenia

Treatments: Other: exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT03453463

FROST

Details and patient eligibility

About

The study determined the effects of predominately resistance type exercise in combination with protein supplements on parameters of sarcopenia and osteopenia (sarco-osteopenia) in older, community dwelling men with sarcopenia and -osteopenia over 18 months.

Enrollment: 43 patients

Sex: Male

Ages: 70+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Sarcopenia according to Baumgartner et al.(SMI: > -2 SD* T-Score)
• Osteopenia at the lumbar spine or hip according to WHO (> -1 SD T-Score)
• community dwelling people
• able to transfer to our lab

Exclusion criteria

• secondary osteoporosis
• history of hip fracture
• medication/diseases that relevantly affect muscle/bone metabolism (last 2 years)
• alcohol abuses of more than 60 g/d ethanol
• cardio-vascular diseases that prevent exercise
• very low physical capacity that prevent exercise in a group setting

SD: Standard Deviation

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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43 participants in 2 patient groups

exercise and protein supplementation

Experimental group

Description:

Predominately resistance exercise training 2-3x week for 18 months; 1.5-1.7 g/kg/d total protein supplementation, Calcium and Vitamin-D-supplementation (i.e. 800 mg/800 IE/d)

Treatment:

Other: exercise

control

No Intervention group

Description:

Calcium and Vitamin-D-supplementation (i.e. 800 mg/800 IE/d)