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Exercise for Young Adults With Cancer (YOUEX)

U

University Hospital Heidelberg

Status

Completed

Conditions

Physical Activity
Cancer
Fatigue
Exercise

Treatments

Behavioral: Exercise - Social Media
Behavioral: Exercise - App
Behavioral: Exercise - closed to patients residence

Study type

Interventional

Funder types

Other

Identifiers

NCT05613699
YOUEX_S932

Details and patient eligibility

About

Over the past decade, importance of supportive care in cancer treatment of young cancer patients has increased. However, most common cancer-related side effects, such as physical deconditioning, psychological problems, infertility, and cancer-related fatigue, are particularly problematic for young adults (AYA). Short- and long-term side effects result in impaired quality of life, social life, and physical activity levels. While there is growing evidence that physical exercise is effective in reducing disease- or treatment-related side effects, programs are generally not tailored to the unique needs of young adults. In addition, social media or web-based programs are rarely structurally integrated into existing care programs. The objective of the Your Exercise Program (YOUEX) study is therefore to address these specific needs and to improve physical exercise services for young people in Germany. To this end, this pilot study presents three approaches to physical activity enhancement, with a particular focus on web-based and cross-regional programs. All three approaches will be evaluated for their feasibility and effectiveness on fatigue, distress, quality of life, and activity levels, as well as sustained effects over 24 weeks. The YOUEX study is an exploratory intervention study in the form of a 12-week exercise program for patients aged 18 to 39 years who currently have or have had a cancer diagnosis within the past 5 years. Eligible patients can choose from three support programs: Social Media Exercise Program, Online Exercise Platform, Supervised Exercise Program. The goal is to recruit 70 to 80 patients over an 8-month period. Evaluation questionnaires will be sent at three time points (T0: start of exercise program, T1: after 6 weeks; T2: after 12 weeks; T3: after 24 weeks) with a short weekly questionnaire between T0 and T2 to assess weekly adherence and changes in fatigue. YOUEX study will collect detailed information on the acceptability and feasibility of different physical activity programs for young people and their lasting effects on fatigue, quality of life and physical activity. Should these be positive, the findings can directly inform health care practice, which would be highly relevant especially in light of the COVID pandemic.

Enrollment

106 patients

Sex

All

Ages

18 to 39 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • cancer diagnosis within the past five years
  • signed informed consent

Exclusion criteria

  • cancer-related cognitive impairment
  • lack of sports clearance from the attending oncologist (e.g. in case of fragile bone metastases)
  • current participation in another exercise intervention
  • insufficient German language skills

Trial design

Primary purpose

Supportive Care

Allocation

Non-Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

106 participants in 3 patient groups

supervised, group-based, online-social media exercise program
Other group
Treatment:
Behavioral: Exercise - Social Media
unsupervised individual home-based training with an online-training app
Other group
Treatment:
Behavioral: Exercise - App
supervised, in-person exercise program close to place of residence
Other group
Treatment:
Behavioral: Exercise - closed to patients residence

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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