Exercise, Heart Failure, and Type 2 Diabetes
Status
Conditions
Treatments
Details and patient eligibility
About
The purpose of this study is to understand the differences in how patients with heart failure respond to exercise training compared to patients with heart failure and type 2 diabetes.
Full description
The investigators will measure exercise capacity in patients with heart failure or heart failure plus type 2 diabetes prior to and following a 12-week exercise training program (5d/wk, 30 min/d, 60-75% VO2max) to determine whether improvements in exercise capacity in response to exercise training are mitigated in patients with combined heart failure plus type 2 diabetes.
Sex
Ages
Volunteers
Inclusion criteria
- ≥50 yr of age
- New York Heart Association class II-III CHF and ejection fraction ≤35%
- receiving optimal medical therapy
- sedentary (≤ 30 min/wk structured physical activity).
- Half of volunteers (n=30) will have a diagnosis of type 2 diabetes (CHF+T2D).
Exclusion criteria
- smoking
- changes in medication ≤6 wk prior to enrollment
- major cardiovascular event or procedure ≤6 wk prior to enrollment
- foot ulcers
- advanced neuropathy
- co-morbidities or other limitations that may interfere with or prevent volunteers from safely completing the exercise training
- fixed rate pacemaker
- type 1 diabetes mellitus
Trial design
Primary purpose
Allocation
Interventional model
Masking
0 participants in 2 patient groups
Trial contacts and locations
Loading...
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal