Exercise in Autoimmune Myasthenia Gravis and Myasthenic Syndromes (MYaEX)

Institut de Myologie, France

Status: Completed

Conditions: Autoimmune Myasthenia Gravis; Myasthenia Gravis; Congenital Myasthenic Syndrome; Lambert-Eaton Myasthenic Syndrome

Study type: Observational

Funder types: Other

Identifiers

NCT05408702

MYaEX

Details and patient eligibility

About

A few recent observational studies show that despite the lack of clear recommendations, many individuals with myasthenia participate in exercise. However, no link has been found between exercise and the severity of myasthenia symptoms, measured by the Muscle Myasthenia Score or the Myasthenia Gravis Composite Score. This suggests that there are other factors that may limit or prevent some individuals from being active, or factors which may facilitate participation in exercise.

Studies in other diseases have shown that there are internal (beliefs, motivation, etc.) and external (cost, accessibility, etc.) factors unrelated to the disease which may play a role in exercise participation.

The aim of this study is to identify factors that facilitate or limit exercise in individuals with autoimmune myasthenia gravis, congenital myasthenia syndrome and Lambert-Eaton syndrome.

Enrollment: 500 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• at least 18 years old
• confirmed diagnosis of MG or SMC or LEMS
• Live in France or its territories
• Provide consent

Exclusion criteria

Trial design

500 participants in 3 patient groups

Autoimmune Myasthenia Gravis

Congenital Myasthenic Syndrome

Lambert Eaton Syndrome