Exercise in Men With Prostate Cancer

University of Manitoba

Status

Completed

Conditions

Prostate Cancer

Treatments

Behavioral: Exercise

Study type

Interventional

Funder types

Other

Identifiers

NCT00834392

H2008:035

Details and patient eligibility

About

The purpose of this pilot study is to compare a walking exercise program (Exercise Group) to standard medical care (Control Group) in prostate cancer survivors receiving androgen depletion therapy (ADT). The central hypothesis of the proposed research is that the walking exercise program will have a positive impact on the bone health, health-related quality of life, and physical function of men with prostate cancer receiving ADT.

Enrollment

30 estimated patients

Sex

Male

Ages

50+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

men aged 50 years or older
diagnosed with adenocarcinoma prostate cancer
will initiate and receive continuous ADT (luteinizing hormone releasing hormone agonist (LHRH) or combination of LHRH and anti-androgen) for at least 12 months after recruitment
Patients will also consent to participating in the study.

Exclusion criteria

severe cardiac disease (New York Heart Association class III or greater)
angina
severe osteoporosis
uncontrolled hypertension (blood pressure > 160/95mm Hg)
orthostatic blood pressure drop > 20mm Hg
moderate to severe aortic stenosis
acute illness or fever
uncontrolled atrial or ventricular dysrhythmias
uncontrolled sinus tachycardia (> 120 beats per minute)
uncontrolled congestive heart failure third-degree atrio-ventricular heart block, active pericarditis or myocarditis, recent embolism, thrombophlebitis, deep vein thrombosis, resting ST displacement (> 3mm), uncontrolled diabetes, uncontrolled pain, cognitive impairment, history of falls due to balance impairment or lost of consciousness, severe neuromusculoskeletal conditions that limit their ability to perform walking exercise (including ataxia, peripheral or sensory neuropathy, unstable bone lesion, severe arthritis, pathological lower limb fractures within 6 months, lower limb amputation).