Exercise in Patients With a Biventricular Pacemaker

Charité University Medicine Berlin

Status and phase: Unknown; Phase 3; Phase 2

Conditions: Left Ventricular Failure

Treatments: Other: Endurance exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT00905944

EA4/063/07

Details and patient eligibility

About

The investigators will evaluate the effects of an exercise program (walking on a treadmill) on the physical performance, the cardiorespiratory function, the proclivity to heart arrhythmias and the quality of life of patients with severely impaired left ventricular function and a bi-ventricular resynchronization pacemaker.

Enrollment: 45 estimated patients

Sex: All

Ages: 18 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Left ventricular failure
• Resynchronization therapy with a biventricular pacemaker
• Ability to understand written German

Exclusion criteria

• Age over 75 years
• Severe cardiac arrhythmia
• All conditions which can be aggravated by an exercise program

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: Single Blind

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45 participants in 2 patient groups

Control

No Intervention group

Intervention

Experimental group

Description:

The patients carry out an exercise program (walking on a treadmill) three times weekly for 12 weeks at a speed corresponding with an intensity of 70% of VO2max.

Treatment:

Other: Endurance exercise