Exercise in Patients With Osteoarthritis of the Hip

Bispebjerg Hospital

Status: Completed

Conditions: Hip Osteoarthritis

Treatments: Procedure: Unsupervised home based exercise; Procedure: Strength training; Procedure: Nordic Walking

Study type: Interventional

Funder types: Other

Identifiers

NCT01387867

HOA-ISMC

Details and patient eligibility

About

According to Danish and international guidelines the recommended first-line of management for people with osteoarthritis consist of exercise, education, analgesic medication, and, if necessary, weight reduction. It is well documented that exercise has a positive effect on pain and physical function in patients with knee OA, but the effect of exercise on hip OA is sparsely investigated.

Aim of the study: To investigate the effects of 1) strength training, and 2) Nordic Walking, and 3) unsupervised home based exercise on muscle function, endurance, pain level, physical activity, and health related quality of life in patients with osteoarthritis of the hip.

The effects of exercise on muscle mass and the mechanisms behind the osteoarthritis, i.e., disease activity, inflammation, and cartilage degradation, are investigated in a subgroup (n=45) of the participants.

Study hypotheses: Strength training will have a greater effect on physical function and muscle strength than Nordic Walking and home based exercise; 2) Nordic Walking will have a greater effect on endurance than strength training and unsupervised home based exercise; 3) Strength training and Nordic Walking will have a greater effect on pain level and health related quality of life than unsupervised home based exercise.

Enrollment: 152 patients

Sex: All

Ages: 60+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

1)Home-dwelling 60+ year old persons with primary, symptomatic hip OA who meet the clinical criteria of hip OA according to American College of Rheumatology (ACR), and who are not on a waiting list for hip joint replacement.

Exclusion criteria

1. symptomatic OA in the knee or the big toe,
2. joint replacement of the knee or the hip,
3. other types of arthritis, e.g., rheumatoid arthritis,
4. previous hip fracture,
5. limitation in physical function to the extent that using public transportation is impossible,
6. co-morbidity that prevents exercising,
7. physiotherapy related to hip problems within the last 3 months,
8. steroid injections in the hip joint within the last 3 months,
9. performing exercise/sports 2+ times weekly, and
10. inability to cooperate.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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152 participants in 3 patient groups

Strength training

Experimental group

Description:

Strength training three times weekly, i.e.supervised strength training twice weekly and un-supervised strength training once weekly for 4 months.

Treatment:

Procedure: Strength training

Nordic Walking

Experimental group

Description:

Nordic walking three times weekly, i.e.Nordic walking twice weekly and un-supervised Nordic walking once weekly for 4 months.

Treatment:

Procedure: Nordic Walking

Unsupervised home based exercise

Active Comparator group

Description:

The home based unsupervised exercise comprised exercises recommended by the Danish Arthritis Association.

Treatment:

Procedure: Unsupervised home based exercise