Exercise in Pregnancy Evaluative Controlled Study (EXPECT)

Swansea University

Status: Completed

Conditions: Pregnancy

Treatments: Behavioral: Physical Exercise Participation

Study type: Interventional

Funder types: Other

Identifiers

NCT02503995

12/WA/0081

Details and patient eligibility

About

This study aimed to investigate whether there are measurable differences in CHANS function in pregnant women who receive only standard antenatal care compared with those who additionally undertake a programme of regular physical exercise.

Full description

The health benefits of physical exercise in the non-pregnant population are generally appreciated but its influence during pregnancy has not been clearly demonstrated. The focus of this proposal is to obtain for the first time a comprehensive understanding of the influence of regular physical exercise during pregnancy on cardiovascular, haemodynamic and autonomic nervous system (CHANS) parameters during pregnancy and following childbirth. This will involve assessing heart rate variability and cardiac stroke volume. This study will allow the investigators to compare CHANS parameters in pregnant women who are randomly assigned into three groups: a 'standard care' group and two groups who engage in a supervised programme of physical exercise (either land-based or water-based). The investigators will assess CHANS parameters at three stages during pregnancy and on one occasion following childbirth. This will allow the influence of regular (weekly) physical exercise on CHANS physiology to be assessed during advancing gestation. The investigators will thus use this study to provide initial evidence of the health benefits of regular and specific forms of antenatal physical exercise.

Enrollment: 90 patients

Sex: Female

Ages: 18 to 45 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Eligible participants were apparently healthy pregnant women aged 18 years or over, with no existing complications of pregnancy at their 12-week dating scan.

Exclusion criteria

• Exclusion criteria were: a history of cardiovascular or chronic respiratory problems, sleep apnoea, or central/peripheral nervous system disorder.

Trial design

Primary purpose: Basic Science

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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90 participants in 3 patient groups

No intervention

Active Comparator group

Description:

Participants not undertaking any additional exercise

Treatment:

Behavioral: Physical Exercise Participation

Water-based exercise group

Experimental group

Description:

Participants assigned to a water-based exercise group

Treatment:

Behavioral: Physical Exercise Participation

Land-based exercise group

Experimental group

Description:

Participants assigned to a land-based exercise group

Treatment:

Behavioral: Physical Exercise Participation