Exercise-Induced Changes in Serum Oncostatin M Levels in Recreationally Active Males

Hacettepe University

Status: Completed

Conditions: The Aim of This Study is to Evaluate the Effects of Acute Exercise on Serum Oncostatin M Levels in Healthy, Recreationally Active Males

Treatments: Other: Moderate-Intensity Continuous Exercise; Other: High-Intensity Interval Exercise

Study type: Interventional

Funder types: Other

Identifiers

NCT07195630

2023/02-27

Details and patient eligibility

About

The aim of this study was to compare the effects of workload-matched acute moderate-intensity continuous exercise (MICE) and high-intensity interval exercise (HIIE) on serum OSM levels on a cycle ergometer in recreationally active, healthy men. Fifteen participants participated in both MICE and HIIE sessions. The HIIE session consisted of 10 x 1 min intervals at 90% of maximal oxygen uptake (VO2max) separated by a 75-second active recovery period at 60 W, whereas the MICE session consisted of a ~21 min exercise session at 55% of VO2max. Blood samples were collected before (Pre) and immediately after (Post) acute MICE and HIIE sessions. Serum OSM levels were measured by the ELISA method.

Enrollment: 15 patients

Sex: Male

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Engaged in regular exercise/training in the last 6 months,
• 18-30 years of age,
• Body mass index (BMI) in the range of 18.5-24.9 kg/m².

Exclusion criteria

• Having a chronic disease that limits exercise,
• Smoking,
• Using any medication or supplement that may affect metabolism.

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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15 participants in 2 patient groups

Moderate-intensity continuous exercise (MICE)

Experimental group

Description:

15 recreationally active males completed the \~21 min of exercise at 55% of VO2max, consisting of a 3-minute warm-up and 3-minute cool-down at 60 W.

Treatment:

Other: Moderate-Intensity Continuous Exercise

High-intensity interval exercise (HIIE)

Experimental group

Description:

15 recreationally active males performed 10 x 1-minute intervals at 90% of VO2max, separated by 75 s of active recovery at 60 W, and a final 3-minute cool-down period at 60 W.

Treatment:

Other: High-Intensity Interval Exercise